• Kogenaru, M. & Tans, S. J. (2014). An improved Escherichia coli strain to host gene regulatory networks involving both the AraC and LacI inducible transcription factors. J Biol Eng, 8(1), 2. [More]
  • Mashaghi, A., Kramer, G., Lamb, D. C., Mayer, M. P. & Tans, S. J. (2014). Chaperone action at the single-molecule level. Chem. Rev., 114(1), 660-676. [More]


  • Mashaghi, A., Kramer, G., Bechtluft, P., Zachmann-Brand, B., Driessen, A. J., Bukau, B. et al. (2013). Reshaping of the conformational search of a protein by the chaperone trigger factor. Nature, 500(7460), 98-101. [More]
  • de Vos, M. G., Poelwijk, F. J. & Tans, S. J. (2013). Optimality in evolution: new insights from synthetic biology. Curr. Opin. Biotechnol., 24(4), 797-802. [More]
  • de Vos, M. G., Poelwijk, F. J., Battich, N., Ndika, J. D. & Tans, S. J. (2013). Environmental dependence of genetic constraint. PLoS Genet., 9(6), e1003580. [More]
  • Nghe, P., Boulineau, S., Gude, S., Recouvreux, P., van Zon, J. S. & Tans, S. J. (2013). Microfabricated polyacrylamide devices for the controlled culture of growing cells and developing organisms. PLoS ONE, 8(9), e75537. [More]
  • Boulineau, S., Tostevin, F., Kiviet, D. J., ten Wolde, P. R., Nghe, P. & Tans, S. J. (2013). Single-cell dynamics reveals sustained growth during diauxic shifts. PLoS ONE, 8(4), e61686. [More]
  • Singhal, K., Vreede, J., Mashaghi, A., Tans, S. J. & Bolhuis, P. G. (2013). Hydrophobic collapse of trigger factor monomer in solution. PLoS ONE, 8(4), e59683. [More]
  • Moayed, F., Mashaghi, A. & Tans, S. J. (2013). A polypeptide-DNA hybrid with selective linking capability applied to single molecule nano-mechanical measurements using optical tweezers. PLoS ONE, 8(1), e54440. [More]
  • Minde, D. P., Halff, E. F. & Tans, S. (2013). Designing disorder: Tales of the unexpected tails. Intrinsically Disord Proteins, 1(1), e26790. [More]


  • Mashaghi, A., Vach, P. J. & Tans, S. J. (2011). Noise reduction by signal combination in Fourier space applied to drift correction in optical tweezers. Rev Sci Instrum, 82(11), 115103. [More]
  • Poelwijk, F. J., Heyning, P. D., de Vos, M. G., Kiviet, D. J. & Tans, S. J. (2011). Optimality and evolution of transcriptionally regulated gene expression. BMC Syst Biol, 5, 128. [More]
  • Poelwijk, F. J., de Vos, M. G. & Tans, S. J. (2011). Tradeoffs and optimality in the evolution of gene regulation. Cell, 146(3), 462-470. [More]
  • Jakobi, A. J., Mashaghi, A., Tans, S. J. & Huizinga, E. G. (2011). Calcium modulates force sensing by the von Willebrand factor A2 domain. Nat Commun, 2, 385. [More]
  • Poelwijk, F. J., T?nase-Nicola, S., Kiviet, D. J. & Tans, S. J. (2011). Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes. J. Theor. Biol., 272(1), 141-144. [More]
  • Kusters, I., Mukherjee, N., de Jong, M. R., Tans, S., Kocer, A. & Driessen, A. J. (2011). Taming membranes: functional immobilization of biological membranes in hydrogels. PLoS ONE, 6(5), e20435. [More]


  • Dawid, A., Kiviet, D. J., Kogenaru, M., de Vos, M. & Tans, S. J. (2010). Multiple peaks and reciprocal sign epistasis in an empirically determined genotype-phenotype landscape. Chaos, 20(2), 026105. [More]
  • Bechtluft, P., Nouwen, N., Tans, S. J. & Driessen, A. J. (2010). SecB--a chaperone dedicated to protein translocation. Mol Biosyst, 6(4), 620-627. [More]
  • Bechtluft, P., Kedrov, A., Slotboom, D. J., Nouwen, N., Tans, S. J. & Driessen, A. J. (2010). Tight hydrophobic contacts with the SecB chaperone prevent folding of substrate proteins. Biochemistry, 49(11), 2380-2388. [More]


  • Kalkbrenner, T., Arnold, A. & Tans, S. J. (2009). Internal dynamics of supercoiled DNA molecules. Biophys. J., 96(12), 4951-4955. [More]
  • Adiciptaningrum, A. M., Blomfield, I. C. & Tans, S. J. (2009). Direct observation of type 1 fimbrial switching. EMBO Rep., 10(5), 527-532. [More]
  • Kogenaru, M., de Vos, M. G. & Tans, S. J. (2009). Revealing evolutionary pathways by fitness landscape reconstruction. Crit. Rev. Biochem. Mol. Biol., 44(4), 169-174. [More]


  • Bechtluft, P., van Leeuwen, R. G., Tyreman, M., Tomkiewicz, D., Nouwen, N., Tepper, H. L. et al. (2007). Direct observation of chaperone-induced changes in a protein folding pathway. Science, 318(5855), 1458-1461. [More]
  • Poelwijk, F. J., Kiviet, D. J., Weinreich, D. M. & Tans, S. J. (2007). Empirical fitness landscapes reveal accessible evolutionary paths. Nature, 445(7126), 383-386. [More]


  • Hermsen, R., Tans, S. & ten Wolde, P. R. (2006). Transcriptional regulation by competing transcription factor modules. PLoS Comput. Biol., 2(12), e164. [More]
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